Nanomaterial applications for neurological diseases and central nervous system injury.

نویسندگان

  • Lijie Huang
  • Jiangnan Hu
  • Shengwei Huang
  • Brian Wang
  • Felix Siaw-Debrah
  • Mark Nyanzu
  • Yu Zhang
  • Qichuan Zhuge
چکیده

The effectiveness of noninvasive treatment for neurological disease is generally limited by the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs cannot permeate into the brain parenchyma because of the blood-brain barrier thus, overcoming this problem has become one of the most significant challenges in the development of neurological therapeutics. Nanotechnology has emerged as an innovative alternative for treating neurological diseases. In fact, rapid advances in nanotechnology have provided promising solutions to this challenge. This review highlights the applications of nanomaterials in the developing neurological field and discusses the evidence for their efficacies.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

iTRAQ-based proteomics profiling of Schwann cells before and after peripheral nerve injury

Objective(s): Schwann cells (SCs) have a wide range of applications as seed cells in the treatment of nerve injury during transplantation. However, there has been no report yet on kinds of proteomics changes that occur in Schwann cells before and after peripheral nerve injury.Materials and Methods: Activated Schwann cells (ASCs) and normal Schwann cells (NSCs) were obtained from adult Wistar ra...

متن کامل

P113: Inflammation and its Role in Neurological Diseases with an Emphasis on MS

Inflammation is an important factor in the pathophysiology of neurological diseases and the physiological response of the immune system against internal and external harmful stimuli. Inflammation is the natural response of the body to damage, which leads to the removal of debris from dead cells and infections from damage and tissue repair. In this study, neuropathic inflammation and its role in...

متن کامل

Ionotropic Glutamate Receptors and their Role in Neurological Diseases

Glutamate is extensively and relatively uniformly distributed in the central nervous system (CNS) and its effects mediated by two distinct groups of receptors including Ionotropic and metabotropic glutamate receptors. Concentration of glutamate in the nervous system is much higher than in other tissues. Glutamate receptors play an important role in synaptic transmission, neural plasticity and n...

متن کامل

Treatment of nervous system injuries by hyperbaric oxygen: a review of molecular mechanisms

Background and aims: The use of hyperbaric oxygen therapy is one of the treatment methods to treat many diseases and injuries such as decompression sickness, wound healing, carbon monoxide poisoning, thermal burns, and nervous system injuries. This article aims to review the possible mechanisms of the effectiveness of this treatment in neurological injuries according to the available studies...

متن کامل

P176: Neurological Diseases: Causes, Symptoms and Treatments

The nervous system is an extremely complex communication system that can send and receive large amounts of information simultaneously. The nervous system has two distinct parts: the central nervous system (the brain and the spinal cord) and the peripheral nervous system (the nerves located outside the brain and spinal cord). The main unit of the nervous system is neural cells (neurons). The rou...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Progress in neurobiology

دوره 157  شماره 

صفحات  -

تاریخ انتشار 2017